EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS141-01291

Organism

Homo sapiens

Tissue/cell

NB4

Coordinate

chr1:161014230-161014700

Target genes

Number: 25
Name	Ensembl ID

RP11	ENSG00000213080
TSTD1	ENSG00000215845
F11R	ENSG00000158769
USF1	ENSG00000158773
ARHGAP30	ENSG00000186517
PVRL4	ENSG00000143217
KLHDC9	ENSG00000162755
NIT1	ENSG00000158793
PFDN2	ENSG00000143256
DEDD	ENSG00000158796
UFC1	ENSG00000143222
USP21	ENSG00000143258
PPOX	ENSG00000143224
B4GALT3	ENSG00000158850
NDUFS2	ENSG00000158864
ADAMTS4	ENSG00000158859
FCER1G	ENSG00000158869
APOA2	ENSG00000158874
TOMM40L	ENSG00000158882
NR1I3	ENSG00000143257
PCP4L1	ENSG00000248485
MPZ	ENSG00000158887
SDHC	ENSG00000143252
C1orf192	ENSG00000188931
RRM2P2	ENSG00000236484

TF binding sites/motifs

Number: 5

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

RFX1	MA0509.2	chr1:161014431-161014447	TGTTGCTATGACAACT	+	6.38
RFX1	MA0509.2	chr1:161014431-161014447	TGTTGCTATGACAACT	-	6.38
RFX2	MA0600.2	chr1:161014431-161014447	TGTTGCTATGACAACT	-	6.26
RFX2	MA0600.2	chr1:161014431-161014447	TGTTGCTATGACAACT	+	6.4
RFX5	MA0510.2	chr1:161014431-161014447	TGTTGCTATGACAACT	+	6.21

dbSUPER

Number of super-enhancer constituents: 12
ID	Coordinate	Tissue/cell

SE_09434	chr1:161013640-161020451	CD14
SE_10418	chr1:161013688-161018603	CD19_Primary
SE_11046	chr1:161006519-161024499	CD20
SE_13858	chr1:161013612-161017634	CD34_Primary_RO01536
SE_14835	chr1:161013718-161017074	CD4_Memory_Primary_7pool
SE_17613	chr1:161010882-161018733	CD4p_CD25-_CD45RAp_Naive
SE_18815	chr1:161013565-161017128	CD4p_CD25-_Il17-_PMAstim_Th
SE_20731	chr1:161013712-161019403	CD56
SE_22624	chr1:161013631-161017754	CD8_primiary
SE_54389	chr1:161013796-161018618	Spleen
SE_60382	chr1:161013786-161019608	Ly4
SE_61824	chr1:161004243-161018982	Toledo

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 1
Chromosome	Start	End

chr1

161014400

161014534

Enhancer Sequence

AAGCCCACTA CCACTGGAAG AATATCCCTG ACCACAAAGA CTAGACTTGG CATTTGGGCC 60
CCATTCTACT GACAGGACTC TTGTTTTGGG GTATCCAGAT TTATATAATC TGTTAGAAAC 120
CCTAAAGCCC AAGTGGATCC TCTTCAAGCA TTCTCTATTT TATTCATCAA GCCTTCCTGC 180
AGAACAACAC TGTTGCTAAA ATGTTGCTAT GACAACTCCA AATCAACTAA GCCTGAGCAA 240
GAAGGGGTAA AAAAAAAAAA AACAGGGTTC TGAAGAAGAG ACAAAGGGGG AAGAATCCAC 300
CTACAAGCTC TGCCTTAGGA CCCTGACACC CAGCCAGAGG GCAGGAAAAA CAAAGAGCTG 360
GGCAGACATG CCTCCAGAAA GAAACAGCTA CACAGTACAA AGCAATAAGA TAATCCCAAC 420
ACAAAAGGGG CAAGATTTTT GGAAATTCTC TACCCATAAG GTCCTCCAAA 470