EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS133-02460

Organism

Homo sapiens

Tissue/cell

melanoma

Coordinate

chr1:154924400-154925320

Target genes

Number: 30
Name	Ensembl ID

RP11	ENSG00000226855
PMVK	ENSG00000163344
PBXIP1	ENSG00000163346
PYGO2	ENSG00000163348
SHC1	ENSG00000160691
CKS1B	ENSG00000173207
FLAD1	ENSG00000160688
ZBTB7B	ENSG00000160685
DCST2	ENSG00000163354
DCST1	ENSG00000163357
ADAM15	ENSG00000143537
EFNA4	ENSG00000243364
EFNA3	ENSG00000143590
EFNA1	ENSG00000169242
SLC50A1	ENSG00000169241
DPM3	ENSG00000179085
TRIM46	ENSG00000163462
KRTCAP2	ENSG00000163463
MUC1	ENSG00000185499
MTX1	ENSG00000173171
THBS3	ENSG00000169231
GBAP1	ENSG00000160766
MTX1P1	ENSG00000236675
GBA	ENSG00000177628
FAM189B	ENSG00000160767
SCAMP3	ENSG00000116521
HCN3	ENSG00000143630
CLK2	ENSG00000176444
FDPS	ENSG00000160752
RUSC1	ENSG00000160753

TF binding sites/motifs

Number: 1

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

RREB1

MA0073.1

chr1:154924921-154924941

ACCCACCCCAACCACAGACA

6.25

dbSUPER

Number of super-enhancer constituents: 24
ID	Coordinate	Tissue/cell

SE_10773	chr1:154923698-154929302	CD19_Primary
SE_11976	chr1:154923436-154929769	CD3
SE_12908	chr1:154924957-154926018	CD34_Primary_RO01480
SE_13480	chr1:154922922-154929708	CD34_Primary_RO01536
SE_14099	chr1:154923732-154929751	CD34_Primary_RO01549
SE_14511	chr1:154922770-154931188	CD4_Memory_Primary_7pool
SE_15677	chr1:154923708-154929430	CD4_Memory_Primary_8pool
SE_15860	chr1:154923725-154926256	CD4_Naive_Primary_7pool
SE_16355	chr1:154923502-154929962	CD4_Naive_Primary_8pool
SE_16929	chr1:154922777-154929871	CD4p_CD225int_CD127p_Tmem
SE_17557	chr1:154922599-154931088	CD4p_CD25-_CD45RAp_Naive
SE_17865	chr1:154918762-154936400	CD4p_CD25-_CD45ROp_Memory
SE_20883	chr1:154923257-154929706	CD8_Memory_7pool
SE_21546	chr1:154923849-154929507	CD8_Naive_7pool
SE_22052	chr1:154923645-154929879	CD8_Naive_8pool
SE_22356	chr1:154922790-154930592	CD8_primiary
SE_24423	chr1:154924723-154925091	Colon_Crypt_2
SE_27195	chr1:154924703-154925304	Esophagus
SE_43530	chr1:154922681-154929856	MM1S
SE_52835	chr1:154924632-154926919	Small_Intestine
SE_53787	chr1:154924022-154925394	Spleen
SE_59728	chr1:154908004-154930021	Ly4
SE_62808	chr1:154907953-154929742	Tonsil
SE_67174	chr1:154922681-154929856	MM1S

Enhancer Sequence

GGAGGAGAAG TGCAAGGAGA AGGGCTGCAC CCAAGAATGG GGCCCCAGCC CACATCCCAG 60
AAACACACAC ATTCAGTCAT GAGCTGGCCC AAAAAGGGGC TCGGGGCAGC ACCAAGTGCT 120
CGGCATTCCC CAGCCTCACT CACTGCGAGG AGGAACTTTC AGGGGCCAGG TTTCCGCTAC 180
ACAGCGCCGC ACCACCAGAC CAAGGCACTG GTTGCAGTAC AAACCTGGTG CCCCGCCTCC 240
AGAAGGTGAG CTAGAGCCTA CGTTTCCCTC CCATCAAGAT CAGCAGCACT TCCTTCCCCA 300
CAGATGAACA ACCCAGATAT TATAATATTA AGGGTGGGAA GAAGGCAAGA GAACAAAGTC 360
CCCTGGGTGC CCACGGGTCA CAGTTATGCC TCCCAGGGTG TCCCTGCAGC TGCCCTCTCA 420
ACTGGACAAC TACTTACATC TCTCAAGCCT TTCTGGCCTT TCCCGCTGGC CCCTGACACT 480
CCCCCGACAC CCGTCTCCCA GCAGCTGCTC ACAGAAGCCC AACCCACCCC AACCACAGAC 540
AGCCTGTCTC CAGGGCACTC TCAGCCTGGA CATCCAGCCC TGGCCACACA GCCTCGGCCT 600
CCTCCCTCTG CCTACTCCCC TTCCATAGGG CCCTGGCCTG CCACCCGCCC CGTGGCTCCA 660
ACTATCCCTC TGAGAGTAAT GCTTCACCTT AGTTATGTCT TTGCTATTTT CAAAACATTT 720
TTATTCTCAT GGTCCCCCCT ACAAGGCAAA AATCATGACG CCCGTTTTAC AGGAGAGGAC 780
AGAGAGGTGA AATGGCATGC CCAAGGTCCC CCAGCTGTCA ACAAAGACAC CTCAACAGGA 840
GGCCAGGGCT CTGAGAGCCT GGTGCCCGTC TGCTCATACC TGCCTTCCCT CTGCCAGTGA 900
GCCCCAGTCC ATTATCTTGC 920