| Tag | Content |
|---|
EnhancerAtlas ID | HS133-00408 |
Organism | Homo sapiens |
Tissue/cell | melanoma |
Coordinate | chr1:16290930-16293400 |
Target genes | | Number: 23 | Name | Ensembl ID |
|
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| EWSR1-FLI1 | MA0149.1 | chr1:16293019-16293037 | CTTTGCTTCCTTCCTTTG | - | 6.33 | | IRF1 | MA0050.2 | chr1:16291221-16291242 | AAAATGAAAATGGAAGAGCAA | - | 6 | | MEF2C | MA0497.1 | chr1:16291053-16291068 | AAGACAAAAATAGCT | + | 6.05 | | Nr2f6(var.2) | MA0728.1 | chr1:16291392-16291407 | GAGGTCAGGAGTTCA | + | 6.22 |
|
| | Number of super-enhancer constituents: 17 | ID | Coordinate | Tissue/cell |
| SE_01987 | chr1:16292569-16293307 | Aorta | | SE_02709 | chr1:16291780-16293317 | Astrocytes | | SE_03452 | chr1:16291596-16293383 | Brain_Angular_Gyrus | | SE_04408 | chr1:16289595-16293617 | Brain_Anterior_Caudate | | SE_05249 | chr1:16287827-16297050 | Brain_Cingulate_Gyrus | | SE_06124 | chr1:16286945-16296922 | Brain_Hippocampus_Middle | | SE_07342 | chr1:16287975-16297074 | Brain_Hippocampus_Middle_150 | | SE_08131 | chr1:16288406-16296945 | Brain_Inferior_Temporal_Lobe | | SE_18522 | chr1:16289418-16295180 | CD4p_CD25-_Il17-_PMAstim_Th | | SE_19255 | chr1:16289594-16294260 | CD4p_CD25-_Il17p_PMAstim_Th17 | | SE_27189 | chr1:16292277-16293531 | Esophagus | | SE_38820 | chr1:16291637-16293540 | HUVEC | | SE_45001 | chr1:16292008-16293377 | NHLF | | SE_45986 | chr1:16291429-16293624 | Osteoblasts | | SE_55849 | chr1:16288535-16295464 | u87 | | SE_61132 | chr1:16274043-16303645 | HBL1 | | SE_67570 | chr1:16288535-16295464 | u87 |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 4 | Chromosome | Start | End |
| chr1 | 16291784 | 16292062 | | chr1 | 16291891 | 16292149 | | chr1 | 16292371 | 16293174 | | chr1 | 16292565 | 16293101 |
|
| | Number: 1 | ID | Chromosome | Start | End |
| GH01I015961 | chr1 | 16288199 | 16293984 |
|
Enhancer Sequence | GGCCAGGCAA GATGGCTCAC GCCTGTAATC CCAACACGTT GGGAGGCTGA GGTGGGAGGA 60
TTGCTTGAGC CCAGGAATTC AAGACTAGCT TGGGCTACAT GGTGAAACCC TGTCTCTACA 120
AAAAAGACAA AAATAGCTGA GCGTGGTGGC GTGTGCCTCT AGTCTCAGCT ACTTGGGAGG 180
CTGAGGCGGA AGGATAGCTT AAGCCTGGGA GGTCAAGGCT GTAGTGAGCC AAGATCACAC 240
CACTGCACTA CAGCCTGGGT GACAGAGCGA GACCCTGTCT CAGAAAAAAA TAAAATGAAA 300
ATGGAAGAGC AATGGGCCAA GGATTTACTA GACACCAGTT CACCAGTTTT CTAAAATGAT 360
GTATTTTACA AGTCAGTGTG GTATTTAAAC AGAGAACAGG CCGGGCACGG TGGCTCACGC 420
CTATAATCCC AGCACTTTGG GAGGCCGAGA TGGGTGGATC ATGAGGTCAG GAGTTCAAGA 480
CCAGCCTGGC CAAGATGCTG AAACCCCGTC TACTAAAAAT AAAAAAAAAT TAGCCAGGCG 540
TGGTGGCACG CATCTGTAAT CCCAGCTACT CAGGAGGCTG AGGCAGGAGA ATCGCTTGAA 600
CCTGGGAGGC GGAGTTTGCA GTGAGCTGAG ATCGCGCCAC TGCACTCCAG CCGGGGCAAC 660
AGAGTGAGAC TCCGTATCAA AAAAAAAAAA AAAAGAATTT CTGCTCATCA AAAACAAAAA 720
ACAATATCCT ACAGTGAAAA GACAAGCCAC AAACTGGAAG TAGGTAGTTA TAACACATAT 780
AACTGACAAA GAATTAGTAT CCAAAATAAG AAATAAAAAA CAAAAAACTA ACAAAATGTC 840
TACAAACCAC CCAATAGAAA AATGAGCAAG ACAATCTGTT GTTTCCGAGA AGATGAAATC 900
TGAATGATCA GTAAGCAACG AAAAGATGCC CAACTCAGAA CCAGGAAAAT GCAAATCAAA 960
ACCACATGAG ATGTCATTGT ACGCCCACCA GATTAGTAAA AATGTTGAAG TCTGAAAATA 1020
CCATTGTTGA GAGGATATGA GGCAAACGGA ATTGTTGAAG GGTAAACTGG GGAAACAGTT 1080
TTGGCAACAA CTTGGCATTA TTTGTTAAGT TGAAGACGCA CATACCCTGT GACTCCACTC 1140
CCAGCTGCAG TCCCTGGAGA GGCTGTGCAT ACATGTCCCG GGAATGTGAA CAGTGGCACT 1200
GTTTGTCTCA GCAAAATACT GGAAACAACC CAAATGTCCA CCAGTAATAG AAAGGATAAA 1260
TAAATTCTCA TACAATGGAA CATTATTCAT CTGTGAAAAT GAAATACCAC TCTATGCAAC 1320
GTGGATTAAT GTCAAGGCAC TGAAGAAAAC AATATGATTA TATTAAGTTC AAAAACCTGC 1380
AGAATTAAAC GGTACATTGT TTAGCAATAC AAACACATGG TAAAACTATA AAGAAAAGCA 1440
AGAGTGATAA AAGCAAAACT CAGGGATGAC TTGGGCCGGG TGAGATCAGG GAGGGGACAC 1500
AGGGGACTCC AAAGGTAACA GTAAGTTCTT TTTGGAAACT GGGTAATGGG TACATGGAAG 1560
ATGTTTCTTG TATCCTTATT CTTTACACTG AACACATTCT TTTGTATGGA GTCAACATTT 1620
AACAAAAACG ATTTACAAAA TTAAACAAGT TCTTTCTTAC TTTAAATCAT TTGCCAAGCA 1680
TTAATTTGGG CTGCTGACTG AGTCACAGTA ACGGGGGAAA ATCCCTGAGG GGCCCACATG 1740
GCCCCGAGAC TACAGAAATG AGAAGTGCTT TGCTCTCTGA GCTCTGGTGA TACAGCTTCC 1800
CATGGGGCAG GCTGGCGAAA TTCGAGTGGA GCCTGCCACT CGGGACAGGA AAGTGACTGC 1860
TTAGGTTAAT AAGTTCCAGT ATAGGAAGTG GTGCGGCTGG GGTGGGGAGA ACAGATTCTA 1920
CTGCCAGACC TTTCAAGACC AGAAGCTGAG TAGATTTTTG ATGTTACAAT GAACCCACTA 1980
AGCCTGCTTT CTGGCCCGCT CTCCACTCGC AGCGGGAATT CCCACCTCTG AGCCTCTGTC 2040
CACACTGCTG TTTAGATATG AGTGAACAAC TCTCAGTTCT AACCATGCCC TTTGCTTCCT 2100
TCCTTTGAAG CCCAGCCCTA CGAACCATCT CTCTTCAATT CATAACAAGC ACGTTTGAAT 2160
CCAAGAGCCT AAGCCCCAGT TTTCTACACG TATCTGTGCT GACTGCATTA CTGAGGTCAA 2220
CCTTAATCAC CCTGGGACTG TCAAACTATT GATGTCCATA AGGATTCTCT GTGCTGGCAT 2280
TCCACACACA CGCAGCAAGG TTCAATGAGC CACAGTACTT ACTCTCTGAC CTCTATTATT 2340
TCAACCATTT AAAAATTGTG GCCACGGGAG GCTGAGGTGG GAGGATCGCT TGAGCCCTGG 2400
AGGTCGAGGC TGCAGTGAGC TATAATCCCA GCACTGCACT CCAACCTGGG CGAAAGAGCG 2460
AGACCCTGTC 2470
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