Tag | Content |
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EnhancerAtlas ID | HS133-00096 |
Organism | Homo sapiens |
Tissue/cell | melanoma |
Coordinate | chr1:2473070-2477800 |
Target genes | Number: 24 | Name | Ensembl ID |
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TF binding sites/motifs | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
EWSR1-FLI1 | MA0149.1 | chr1:2474584-2474602 | GGAGGGAAGGGAGGAAGA | + | 7.45 | KLF16 | MA0741.1 | chr1:2477727-2477738 | GGGGGCGGGGC | - | 6.02 | KLF5 | MA0599.1 | chr1:2477728-2477738 | GGGGCGGGGC | - | 6.02 | MYCN | MA0104.4 | chr1:2476128-2476140 | AGCCACGTGGCC | + | 6.37 | MYCN | MA0104.4 | chr1:2476128-2476140 | AGCCACGTGGCC | - | 6.37 | MYCN | MA0104.4 | chr1:2473218-2473230 | GGCCACGTGGCC | + | 7.22 | MYCN | MA0104.4 | chr1:2473218-2473230 | GGCCACGTGGCC | - | 7.22 | RREB1 | MA0073.1 | chr1:2477666-2477686 | GGGGAGTGGGGGGTGTGGGG | - | 6.54 | ZEB1 | MA0103.3 | chr1:2473540-2473551 | GGGCAGGTGGG | - | 6.14 | ZNF263 | MA0528.1 | chr1:2477658-2477679 | GGGGGAGCGGGGAGTGGGGGG | + | 6.63 | ZNF263 | MA0528.1 | chr1:2474713-2474734 | GAGGGAGGAGGAACGGGAGGG | + | 7.37 | ZNF263 | MA0528.1 | chr1:2474581-2474602 | GATGGAGGGAAGGGAGGAAGA | + | 7.4 | ZNF263 | MA0528.1 | chr1:2474716-2474737 | GGAGGAGGAACGGGAGGGGGC | + | 7.66 | ZNF740 | MA0753.2 | chr1:2477671-2477684 | GTGGGGGGTGTGG | - | 6.03 |
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| Number of super-enhancer constituents: 16 | ID | Coordinate | Tissue/cell |
SE_11213 | chr1:2476697-2485103 | CD20 | SE_17026 | chr1:2477043-2477655 | CD4p_CD225int_CD127p_Tmem | SE_17496 | chr1:2476790-2482869 | CD4p_CD25-_CD45RAp_Naive | SE_17885 | chr1:2476630-2482836 | CD4p_CD25-_CD45ROp_Memory | SE_19265 | chr1:2476965-2477653 | CD4p_CD25-_Il17p_PMAstim_Th17 | SE_20157 | chr1:2476692-2482555 | CD56 | SE_22447 | chr1:2476677-2482767 | CD8_primiary | SE_25218 | chr1:2474834-2482947 | Colon_Crypt_3 | SE_31873 | chr1:2474681-2483779 | Gastric | SE_41959 | chr1:2473048-2473804 | LNCaP | SE_41959 | chr1:2476765-2477633 | LNCaP | SE_42866 | chr1:2475405-2484449 | Lung | SE_50461 | chr1:2475229-2484208 | Sigmoid_Colon | SE_53028 | chr1:2476814-2477650 | Small_Intestine | SE_53615 | chr1:2475968-2483887 | Spleen | SE_55443 | chr1:2476878-2477621 | Thymus |
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| Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | Number of disease enhancers: 3 | Chromosome | Start | End |
chr1 | 2474919 | 2477467 | chr1 | 2474187 | 2474281 | chr1 | 2474604 | 2476279 |
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| Number: 1 | ID | Chromosome | Start | End |
GH01I002541 | chr1 | 2473049 | 2473804 |
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Enhancer Sequence | ATGTTTCACT ACTTGTGAAA AAGATGAAAT TCAAGTTTCA GCGTCCATAA ATAACATTGT 60 ACGGAGACAC AGCAGGGCGC CACACCCGAT GCTATCCAGG AAGGCCACCT CCTGGCGTGA 120 CGCCAGTGGC GTGGTAGGAC AGAAGCCTGG CCACGTGGCC TGCAGTGGTT ACTGCTGGGC 180 CCTCTTCATA AGCACTGGTC CCACCCGCAG TGAAGGACTA CCTGCCCCAG GCAGAGCCTC 240 CCACGATCGA TCGCTGTCCT CACCGCCCCC GGGGGGTGCC CCATTCCTCT CACTTCTGGG 300 GCTGATGTGG GAGCCTCAGG AGGGGACTGA GTGAGTGTGC ACTTGAGTGT GGCCACACCG 360 TCCTGAGGCT TCGTCATCGT GCCCATTGGA CAGGGTGGCA AACTGAGGCC CATGGAAACC 420 CAGGGCCCAG CTGCCAGGTG GAGGCCGAGG CCAGAGAGAA CCCTGGGCTA GGGCAGGTGG 480 GCAGCCTCAC CCACCCGGGT CAGGCTCCTG CTTTGCTCAT GTAACCCTCA CGCTGGCCAC 540 AGGCACTTCC TCAGGTCCCT GCCGCAGAGC ACGCGCACGG GTCTGCTCTT CCACCGCTGG 600 GAAAGACCTA CTTTGCACTG AAAAGCGTCC CAGCTTCCCT CCCGGCTAGA CTGGCAGCTC 660 CACATGACTC GCTGGGGTCC TGGGCTGACT TTTGGCCTTT TTCCCCAACT GATTATTGAG 720 GGGGTGGCCT AGCTGATCTT TGGGGCTCCA CAAACAGACA CAGGGTGGGG TCAACGTGTC 780 TTCCACAGGG GGCAGAGTCC AGGGGGAGCA GCAGCCTGGA GCAGTGCTGA GGGCTTTGCG 840 GGATGGCAGC TCGCTTGCTC CTGAAGCAGA TTAGGCCCTG TGAGGGGCTG GGGTCTGGGC 900 CATACTGCTG GGAGGCGGGG GGGTGCTGCT TGTTGTCAGT TACCTGGGAA GCCCTGGGTG 960 GGGTCCGGCA GCTCTGGGAC TCTGGGTCTG GAAGTCCATT CTCTTGTCCC ACTGGCCTGC 1020 AGGTGTTTGG CCCTTCCTGT GGCCCTGGCC TTGTTGCACT GGCCCTGTGC CAGCACCCCC 1080 CATCTGGTGC CCTAGCTCTG CGAGCACTAT CTGGCCAGGG TGTGGGGGAC CCTCTGTCTA 1140 TGAGCCTCTG TCATCCACGT GTAGGGGGAC CAGGGAGATC ACAGATGTGG GGCTCAAGCC 1200 CCAGGCCCCA GTGATCACTT CTCTCTGAGC CTTGGATCCC AGCCCTTCCC TTGATGTGCC 1260 GCCCCAACTC TTACAGGGGA TGCTGGCCTT TATCAGCACT CTATTTGGGG TGTGGTACCG 1320 AGTGGGGCTC CCATCCCCAC CACCACCCCC ATTACGATGG GCCAGCTGTC TCAGGTAGGG 1380 GCTTCCAGCC CAGCGTGGGG ACCCTCGGCA GTGACCAGCA GGGAGGACCC ATGCCTGGGG 1440 CACCCCCACA GCCATGGATG GGGGTCTCCG GGGACCTGCT GCAGCACAGT GGATATGGCA 1500 CCCCTGTCAC AGATGGAGGG AAGGGAGGAA GAGGCCTGGC GAGCTTAGGC AGAGGAGAGG 1560 TCAGGCTGCC AGCCCAGCCG GGCAGGAACC ACCCTTTTTC ATTAAGTGAG CCCCCGGGCC 1620 GAGAGTTCTG CTGGTCCCGT GGTGAGGGAG GAGGAACGGG AGGGGGCTCT GGGAGTCTGC 1680 GCTTCCTCCT CTAGTTGCCC CCTAGGTCTG GCAGAGACCT TCAGCCTCTT GTCCCCACCC 1740 CCAGGACTGA GATGCATCCT GGCTTCAACC AGGGGAGACT CTGGCTTCTG GAGGGCAGCC 1800 ACCCTCTGGA CTTGAAGGTG CCCAGGGCAG GTTCCAGAAG GTCCTGCTTC CCCCCAGTAC 1860 CCCGGCCCAG CCCCTGGAGC CCCTGGGAAT GTGTTCAGCC TCCTGCTCAG TAGCCCTCAG 1920 CCCACTGGGC TCCAGCCCCA TCAGGCAGCT CCCCCGCCCT GGAGCCACCC TCAGCAGAGT 1980 GGCAGCCACC CTCAGCCCTC CCTCGCCTGT GGCTCCTGCG TGAGGTGGGG GAGGGGGAGC 2040 CCGGCACTGC TTGCCTGTGT CAGGGCTCGG GGCTGGCACC GAGGCTGTGT GCTGCCCCAG 2100 GCACCCGCCT ACCTCCCCTG CCTGGAGGGG CATTTGGGCT GGAGCCCGCT CCGGGTGGGT 2160 TCCCACATCC ACCCCCCTCT GCGGACATTC ATCCTGCACA AAAGGCGCGT GCGCGGCAAC 2220 AAACTCATTC GCCACGGGCT GCCTGGGCTT TGTGTGCTGA GCTCCGGCCT CAGAGGCCAT 2280 CTGGGGAGCA GTCGTCCCAG CGGGCGGCAG GGCCCCCTCC AGGCTGCCTT TGAGGCCTGG 2340 GAAGCAGCCG AGGCTCCCTG AGCAACCGCG CTGGAAACCG CACACATCTG GCCTGTCCAG 2400 TGCCTTCCAG TTCCCGCAGC CTCCTGGCTG TCCCCTGCAC GCTCTGGCCC TGGCATGGCA 2460 CTAGGTGCCA GGAGGGGACC AAGGCAGGCG CCTGCCTCCC TGCCCTACCC CTGATGCAGG 2520 CTGTGTGCAC ACGGCCCAGT GGGGAGGGCT GTGGGCACGG GGTTCAAATC TGGGGAGTAC 2580 CCCTCAGTAG GTGGGCCCTC TGGGGCTCAG CTTCCTCATC TGTGCAATGC AGCTGATAAC 2640 GCTCCCACCC AAGGCCTGTG CTGAGGACGG AGAGTGGATG AGCGCCAGGC ATGTGCAGTG 2700 GCCTCGGCAC GCAGACCCCT GCCCCAGGCA CTGCCCGGCT CTGCTTCTTC TCGCCTTCAT 2760 TCGGTTTCCT GGGTGGGCGA CCCCTGCCCG TGTTCCAGGC TTCCTGGAAA CTGGCTGGGG 2820 GTCAGGGAAA GGCCAGCTGG CCGCAGGCAG CTCTGCTTAG AGCTGGGCCC ACCCCTGCTC 2880 GGTGTGGGTG CGGCAGCTGT GGTCCTGCCC CACTCTCAGG ACTCTGAGCA GCTTCTGCCT 2940 GGCCTGTATG CAGTAGGTGC TGAGTAAGTG AGCACTTGCC TCGAGGCCCT CAGCCCTGAG 3000 CACCTCCAAG TGTGATCTCA GCCCTGGATC TGGCTTGGGT CTGCCCAGCT GTGGGCGCAG 3060 CCACGTGGCC TGGGGTCGAG GGGGGGTTAC TAGCAACCCC CAGCAAGCTC CTCTGCTGAG 3120 CACGCCCTTC CCCAGAGGGC TAGAGGCCAG GACAACAGTG AGCCGGGGCT CCAGGACAGC 3180 CTGCCTGGCG TGGCGGGCAT TTCTGAGTCT GGGCGGTTGG ATGCGGTAGG GGGCATGGAG 3240 TGGGGTGTCC GAGGGGTCTT TCCACTCAGG AGACCCTTCC TGGCCAAGCG ACTTCTGGGG 3300 CCACAGCTCA GCAGACAGGG CCTCTGCAGA GGCGTCCCTG CCCCCAAGCA TGCTGGGGGC 3360 GTCCTTGAGA GGGTGTCCTG CAGACCCAGA GATAATCCGG GCTTTGAGAG GCTGTGAGAG 3420 GCTGGCCCGA GGACTTTCCC ACAGCCCCAC AGAAAGGGCC GGCAGCCAGC TGCTCACCCA 3480 CAAAAGGCTC CCGGCCATTC ATGGCCTCAG GCAGGCGGGG CTGTCGGAGC GGCAGCCACA 3540 GCCTACCTGG CCACCCCCAG CAGGACTTTC GTGACAGGGA GGCACCTCCC TTCTGGCCAT 3600 GGGGGCAGGA GGTCTCCAGG GCATAGGGGT AGTCTTGTGC AGCCACCCAG GCCAGCTGCT 3660 ACCCCCTCTC TTTTGGCCCG AGACTGGCAC CCTTCCTGGG CCTGTCATTT ATCATGGGTG 3720 CCTGGGTAAA GGATGGCTCA GGAGGACCCT GCAGGCACCC ACTACCATGC CTGGCGCCGT 3780 GCCTCCACCG TCACACTACC CATTGCTCGC CCCCACACGC TGGCCATGAG TCCCCAGGGC 3840 TGGCACCTTC CTTGCTTCCA AGTCTGGCCT GCACGGCTCT CACACCCTTT GCAACCATCT 3900 TCTTGCCCAC CCAGCAGCCC ACCCTGTCAG TGTAGGGGGC AGGAGAGGGA CCTGGTGGGG 3960 CAGTGAGCTG GGTAAGGCCT CCTCCCTGGA CCTCAGTCTC CTTGTCTGAG GTGTGGGACA 4020 GCACTGCTGC CTCCCAAGGC TGATGGAAGG ACCCCCAAGG GCGGCTGGTT AACAAATACC 4080 AGGTTTGGAG AAGCTGGGGT GTGGGGCTGC TGCCTGGAAT TAACTGCCCA GAGCACCTCC 4140 AAGGATGACC TTTTAATATG AGAGCCAGCC CAGGGGAGGG AAGGGTCGGG GGCTTCCTGG 4200 GGGAGGTGGC CGCTGGCCTG GATTATCAGG AAGTGCAGGA GGAGGGTGGG GGCTTCCTGG 4260 AGCAGTGGCC CTGGCCCCCC TGTGCAGTAG CTGCGGCTCA GCCCCTTCCC TGGCCTGTCT 4320 CCCTGTTGCT TCCACAGCTG GAGCTGCCTC TGCGGCCCCT GTCCTCACCC CTGAGGAGGC 4380 CAGGCCCGGG CAGGTGCCTG GGCTGGGGCT GCTCCTGGCC AGGCTGGAAG ACTGTCAGAT 4440 GGAGGACAGG TCAGGTGGTC GGAAAGCTGG GGACAGGGAG GGAGCAGGTT TGACGGAGGG 4500 ACGTATGGGC AGGCTCCTCC TCCCGGTCAG GTCCCACGTG ACCCCCCAGC CACGCCTACC 4560 CACATCGCCC TGCTGGAGGC CGGGGGCGGG GGGAGCGGGG AGTGGGGGGT GTGGGGGGTG 4620 AGGGGGGTGG GGGTGGGGGT GGCCCGGCCC GGAGCTAGGG GGCGGGGCCG TGCTTCTTCT 4680 GGCCCTGGCC TCCAATTGGC TGCCGGGCGT GGGAAAGCGT GCACCACTGC 4730
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