Tag | Content |
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EnhancerAtlas ID | HS129-03647 |
Organism | Homo sapiens |
Tissue/cell | MCF10A |
Coordinate | chr1:226822590-226824520 |
Target genes | |
TF binding sites/motifs | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
EWSR1-FLI1 | MA0149.1 | chr1:226822922-226822940 | CCTTCCTTCCTTCCTTCC | - | 10.83 | EWSR1-FLI1 | MA0149.1 | chr1:226822926-226822944 | CCTTCCTTCCTTCCAGAC | - | 6.49 | EWSR1-FLI1 | MA0149.1 | chr1:226822872-226822890 | CCCTCTTTCTTTCCTTCC | - | 6.63 | EWSR1-FLI1 | MA0149.1 | chr1:226822909-226822927 | CCTTCCTTTCTTCCCTTC | - | 6.85 | EWSR1-FLI1 | MA0149.1 | chr1:226822892-226822910 | CCTGCCTTCCTTCTTTTC | - | 7.36 | EWSR1-FLI1 | MA0149.1 | chr1:226822914-226822932 | CTTTCTTCCCTTCCTTCC | - | 7.41 | EWSR1-FLI1 | MA0149.1 | chr1:226822905-226822923 | TTTTCCTTCCTTTCTTCC | - | 7.67 | EWSR1-FLI1 | MA0149.1 | chr1:226822888-226822906 | CCTTCCTGCCTTCCTTCT | - | 8.38 | EWSR1-FLI1 | MA0149.1 | chr1:226822876-226822894 | CTTTCTTTCCTTCCTTCC | - | 8.46 | EWSR1-FLI1 | MA0149.1 | chr1:226822880-226822898 | CTTTCCTTCCTTCCTGCC | - | 8.48 | EWSR1-FLI1 | MA0149.1 | chr1:226822918-226822936 | CTTCCCTTCCTTCCTTCC | - | 8.57 | EWSR1-FLI1 | MA0149.1 | chr1:226822884-226822902 | CCTTCCTTCCTGCCTTCC | - | 9.25 | SRF | MA0083.3 | chr1:226823548-226823564 | TTCCCAAATATGGCCA | - | 6.05 | SRF | MA0083.3 | chr1:226823548-226823564 | TTCCCAAATATGGCCA | + | 6.12 | ZEB1 | MA0103.3 | chr1:226823652-226823663 | GGGCAGGTGGG | - | 6.14 | ZNF263 | MA0528.1 | chr1:226822910-226822931 | CTTCCTTTCTTCCCTTCCTTC | - | 6.01 | ZNF263 | MA0528.1 | chr1:226822918-226822939 | CTTCCCTTCCTTCCTTCCTTC | - | 6.31 | ZNF263 | MA0528.1 | chr1:226822884-226822905 | CCTTCCTTCCTGCCTTCCTTC | - | 6.33 | ZNF263 | MA0528.1 | chr1:226822914-226822935 | CTTTCTTCCCTTCCTTCCTTC | - | 6.41 | ZNF263 | MA0528.1 | chr1:226822872-226822893 | CCCTCTTTCTTTCCTTCCTTC | - | 6.72 |
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| Number of super-enhancer constituents: 22 | ID | Coordinate | Tissue/cell |
SE_03869 | chr1:226820788-226823038 | Brain_Anterior_Caudate | SE_04801 | chr1:226819476-226822967 | Brain_Cingulate_Gyrus | SE_04801 | chr1:226823325-226826897 | Brain_Cingulate_Gyrus | SE_05781 | chr1:226818536-226856817 | Brain_Hippocampus_Middle | SE_09326 | chr1:226821210-226822837 | CD14 | SE_10887 | chr1:226818468-226824061 | CD20 | SE_14432 | chr1:226821996-226824150 | CD4_Memory_Primary_7pool | SE_16856 | chr1:226823222-226823743 | CD4p_CD225int_CD127p_Tmem | SE_17296 | chr1:226819194-226825084 | CD4p_CD25-_CD45RAp_Naive | SE_17765 | chr1:226820318-226824442 | CD4p_CD25-_CD45ROp_Memory | SE_18263 | chr1:226819934-226825420 | CD4p_CD25-_Il17-_PMAstim_Th | SE_19160 | chr1:226820781-226824212 | CD4p_CD25-_Il17p_PMAstim_Th17 | SE_22315 | chr1:226820328-226822822 | CD8_primiary | SE_26570 | chr1:226820372-226823751 | Esophagus | SE_42228 | chr1:226821191-226822877 | Lung | SE_54498 | chr1:226818464-226823018 | Stomach_Smooth_Muscle | SE_54498 | chr1:226823062-226824485 | Stomach_Smooth_Muscle | SE_58303 | chr1:226819953-226937809 | Ly1 | SE_59629 | chr1:226819233-226928465 | Ly4 | SE_60416 | chr1:226819368-226929640 | DHL6 | SE_61009 | chr1:226812849-226900772 | HBL1 | SE_62233 | chr1:226813614-226929647 | Tonsil |
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| Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | Number of disease enhancers: 1 | Chromosome | Start | End |
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| Number: 2 | ID | Chromosome | Start | End |
GH01I226632 | chr1 | 226820348 | 226823790 | GH01I226636 | chr1 | 226824423 | 226825119 |
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Enhancer Sequence | AGGAGAACAT GGGGGTGAAG GGTGAGCTGA AGCCCGGGCC TCGCCCTCCC CACTGCGGCC 60 CGGGGCCTGG GTGACCAGGT GGGGAGGCTC GCTCAGGCCG GACAGTTGGG TGCCTGCAAT 120 TCCAATCCCC ATTTTCAGAC AGGCAGCAGA GCCGGCCCAA GAATGGCCAT GCCTGGGCAG 180 AGGGCATCGG GTTCCAGGGT CGGCGACCAC CCTTCTGTGT GGGCAGCAGC AGGCACCCCT 240 TCACCCCCTG ACTCTGGCCT GCACACTTTC CACTCCTTCC CTCCCTCTTT CTTTCCTTCC 300 TTCCTGCCTT CCTTCTTTTC CTTCCTTTCT TCCCTTCCTT CCTTCCTTCC AGACAGGGTC 360 TTACTCTGTC GCCCCAGCTG GAGTGCAGTG GTGCAACCTC AGCTTACTGT AGCCTTGATC 420 TCCTAGGCTC AAGCGATCCT CCCACCACAG CCTCCCGAGT AGTTGGGACT ACAGGCATGC 480 ACCACGATGC CCGGCTAACT TTTTGTTTTT TATTTTTGTA GAGACAGGGT TTCACTATGT 540 TACCCAGGCT GGTCCCAAAC TCCTAAGCTC AAGCCATTCT CCTGCCTTGG CCTCGGAAAG 600 TGCTGAGATT ACGGGCATGA ATCACACTGC ACCTGGGCAA ACTTTCCACT CTTTCTAGAC 660 CACAACCCAA TCTGGGGCCT CGCCCTTCCG CCTCCTAGAA CCTGACTCCT CCCAAACACT 720 CTGCAGGGAA CCACAGTGAA GGGGAAGGTG CCCAGGAGCG TCCAAACTAT CCCGGGGCGG 780 GGGTGGTGAA GAACCTGTTT CAAATGCACA CAGCACCCCC ACCCCAGCAG CACAACCCCT 840 GCAGATTCAG CGTGGGCAGA CCCTATAGGG CCTTCCCAGC CTGGCCCAGG GATAGTGGGC 900 ACCAAAGAGC CTGCCCCTCC TGGGTGAGCT CAGAGCCTCT GCATGGGAGC GAGGCGCTTT 960 CCCAAATATG GCCACACATA CCCCTGCATC ACCTCAGTGG GGCCAGAGGA AGGCCGGGGG 1020 CACAGAAAGG GCTCAGGTGA CATTCCAGCT TCCAGCAGTG CAGGGCAGGT GGGGCCCCTG 1080 GCGAGGCTGA GCCCAAAAAA GGGGCTTCCT CTTCGCAGGT GGAAAACAAC AGACCCAAGC 1140 TGATTTGGCC TCTTTCTAGA CCTTAAGGGA GACCCCAAAA AGTGTAGAAC AAAATGCTTT 1200 TCCAAGAAAT AAAAGCAGAA GTGTTGAAGA AGGGTGGGAA CGGCTTTGAG ACAGAGCTCT 1260 GTGGCCTTAA GTTCTCCCAG GCTTGGCCCC TGGGGTCAGG CAGCCAGGCA GCACCCCCAT 1320 CGTCCAGAGA GGCAGCTGGG GCAAAGGGGG CTCTGGCAGG TGGCAGGAGG ATGCTTCATC 1380 AAGTGGAAAG GAGAGGCCAC AGGAGGAGCT GAGGGTCTGG GGGACAAGGA GAGCAAAGAA 1440 CATTCCGAGA AGGACCGAGC TCCCTGCTAG GGGCACAGCA AAGCCTGAGT CTCCTCTCTG 1500 GGTGTGCCAC CCCCTCCTCG CAGCCATCCT CTCCAGGCGC CCCGCAGGGA ATGACATGCA 1560 GAGCAAGGTA GACCATCTGC CTGAGGAGGC CTGGTGGTGT AGTTTGCAGA AAGATGCACC 1620 GCCCTGCTGG CTGCCTCAGG GCTGACCCTA TGAGTTCCTC CTGCTGGCTC CGCAGCCTTC 1680 TCTGTGGGCA TAGGCTGAGG CTGAGGCCAC CTCCATGTAA GACCCCATAC AAGAGGACCT 1740 CCACAAGAGA GTCCCTACGA GAGGGGCTGC TTTCCTGAAC TACCTACACA GCTGCAGGGA 1800 GCCGCAGGAT CCCGCTTCAC ACCCACCCAC CCATGGGATT AGCCAGCCCC AGGACTGCAG 1860 CTCTGTGTGT GTGTGTGTGT GTGTGTGTGT GTGTGTGTGT GTGTGAGACT GGGAAAGGCA 1920 TGCATGTTTG 1930
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