Tag | Content |
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EnhancerAtlas ID | HS084-00266 |
Organism | Homo sapiens |
Tissue/cell | HCT116 |
Coordinate | chr1:94779870-94797100 |
TF binding sites/motifs | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
EWSR1-FLI1 | MA0149.1 | chr1:94790688-94790706 | AAAGGGAAGGAAGGAAGA | + | 6.04 | EWSR1-FLI1 | MA0149.1 | chr1:94789007-94789025 | CCTTCCTTCACTTTTTCC | - | 6.23 | EWSR1-FLI1 | MA0149.1 | chr1:94790696-94790714 | GGAAGGAAGAAAGAAAAA | + | 6.2 | EWSR1-FLI1 | MA0149.1 | chr1:94790692-94790710 | GGAAGGAAGGAAGAAAGA | + | 8.26 | FOS | MA0476.1 | chr1:94788803-94788814 | TCTGACTCATT | + | 6.32 | FOXP2 | MA0593.1 | chr1:94791958-94791969 | TTTGTTTACAT | - | 6.14 | HNF1A | MA0046.2 | chr1:94781326-94781341 | AGTTAATTTTTAATT | - | 6.49 | IRF1 | MA0050.2 | chr1:94790732-94790753 | AGAAAGAAAAAGAAAGAAAGA | - | 6.14 | IRF1 | MA0050.2 | chr1:94790705-94790726 | AAAGAAAAAAAGAAAGAAAAG | - | 6.5 | IRF1 | MA0050.2 | chr1:94784757-94784778 | AGTTTCTTTCTCTTTCTTTTT | + | 7.33 | KLF16 | MA0741.1 | chr1:94793070-94793081 | GGGGGCGGGGC | - | 6.02 | KLF5 | MA0599.1 | chr1:94793071-94793081 | GGGGCGGGGC | - | 6.02 | LMX1B | MA0703.2 | chr1:94789153-94789164 | TTAATTAAAAC | - | 6.14 | MEF2A | MA0052.3 | chr1:94780527-94780539 | TCTATAAATAGA | + | 6.74 | PRDM1 | MA0508.2 | chr1:94790958-94790968 | GTGAAAGTGA | - | 6.02 | RREB1 | MA0073.1 | chr1:94795317-94795337 | CCCCACCCCCACCCCCACCC | + | 6.27 | STAT1 | MA0137.3 | chr1:94781531-94781542 | TTTCCAGGAAA | + | 6.62 | Stat4 | MA0518.1 | chr1:94781531-94781545 | TTTCCAGGAAAGGG | + | 7.64 | TFAP2C | MA0524.2 | chr1:94787305-94787317 | TGCCTTGGGGCA | - | 6.62 | ZBTB18 | MA0698.1 | chr1:94781938-94781951 | ACACATCTGGAAT | - | 6.02 | ZBTB18 | MA0698.1 | chr1:94783574-94783587 | TTTCCAGATGTGC | + | 6 | ZNF263 | MA0528.1 | chr1:94795312-94795333 | CTCTCCCCCACCCCCACCCCC | - | 6.06 |
|
| Number of super-enhancer constituents: 9 | ID | Coordinate | Tissue/cell |
SE_34380 | chr1:94781130-94786058 | HCT-116 | SE_34380 | chr1:94787137-94794227 | HCT-116 | SE_34380 | chr1:94794236-94796445 | HCT-116 | SE_38077 | chr1:94784174-94786935 | HUVEC | SE_38077 | chr1:94787246-94796050 | HUVEC | SE_45763 | chr1:94787902-94796410 | Osteoblasts | SE_47310 | chr1:94783371-94797039 | Panc1 | SE_52228 | chr1:94788316-94794071 | Skeletal_Muscle_Myoblast | SE_64027 | chr1:94788252-94794085 | HSMM |
|
| Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | Number of disease enhancers: 7 | Chromosome | Start | End |
chr1 | 94787153 | 94787197 | chr1 | 94792358 | 94792531 | chr1 | 94793801 | 94793969 | chr1 | 94792635 | 94794112 | chr1 | 94792807 | 94793133 | chr1 | 94795413 | 94796000 | chr1 | 94788386 | 94788592 |
|
| Number: 5 | ID | Chromosome | Start | End |
GH01I094322 | chr1 | 94787153 | 94787197 | GH01I094321 | chr1 | 94787241 | 94794560 | GH01I094329 | chr1 | 94794912 | 94796210 | GH01I094315 | chr1 | 94781354 | 94786558 | GH01I094331 | chr1 | 94797087 | 94797992 |
|
Enhancer Sequence | TCAGAGTCAT TGCATTAGGC AAGCAGTGAC CATCTGGGCG GGCATCAGGG ACATGAATAA 60 GTATTGGGGT TAACTGAACC CAAGACTCCA TGATTCTGGG GGATTGTGCT CCCTGAAGTC 120 ATCAGTAGCT CCCTGAACAA AGAACCCACA GGTCTTTCTC ATTTATAACA CTTACAGATG 180 AAGTTTTCTC TCTCCTTTCC CTCGGCTTAA GAGGCAGCAC TGAGTTGACC AAGTCCTCCA 240 CCCATTCTCT GACCACCACT CAGACAGACC CCTTTGCTGG CTCCTCTTTC TCTTGCTAGC 300 CCTTTAAACC TGTGTGTTGC CAAACAGTTT TTTTACTTTA ACACTCTCTC TAAATGCCTG 360 TTAATCATTA TCTAAGATGA TAGCATGAGA AAGATTGCAA AAATGCTAGG AGTAATATTT 420 AAAAAGCACA ATACATTTTG CTTTGCATGT TGGTGAAGTC TCCTGATTTT TATTCAGAAG 480 ACCTAGGCTT GAGCTACTTA CCCATTTTGT GTCTGGGGTC AAGACTCTTA ACTTCTCTAG 540 GCTTCTATTT CTGCATTTAT AAAACAAGGA GAATAATATC TCACCTTACA TGCATTATCT 600 TAATGTATGA GGTTTGGGTG ATACATGTGT GGATAGGTTT TATAAAATAT CATCTGATCT 660 ATAAATAGAG ATTTTATTAT GATAGACCAT AAAAAGGGGT CACTAAACCA TTGTCTATAG 720 AAGATAATAA TTGATATAGG GCTGGGCATG GTGGCTTACA CCTGTAATCC CAGCACTTTG 780 GGAGGCCAAG GTCGGCAGAT CCCTTGAGGT TAGGAGTTCA AGACCACCCT GGCCAACATG 840 GCAAAACTCT GCCTGTACTA AAAATATAAA AATTAGCCTG GTGTGGTGGC AGGTACCTGT 900 AATCCCAGCT ACTCAGGAGG CTGAGGTACG AGAATCTCTT GAACCCAGGA GGTGGAGGTT 960 GCAGTGAACT GAGATAGCAC CACTCCACTC CAACCTAGGC AACAGAGCAA GACCCTGTCT 1020 CAAATAATAA TAATAATCAT AATAATAATT GGTATAGGCA ATTGTCTTTT CATGTCTGTG 1080 TCTGTAAGGA GAAAGTCGTA CTTGTAGGCC TGTGATTGTT TTTAGGCCCT CTCTCAAGAT 1140 CCAATCAAAT CAGTAATGCA CTGTAACTGC CCATAGACCC AGGCTTATAG CCTCAAATAA 1200 TCTACAAATA TGCAACCAAA ATAATTAAGC TGAAGTGCTT CTTTTGTCCA AATAAATCAG 1260 GCCACTTTTT CATATATAGA AATTAACAGT TCCTGAATCT TTTTTTTTTT TTTTTGACAG 1320 GTTCTTGCTC TGTTGCCCAG GCTGGGGTCT AGTGGTACAA TCATGGCTCA CTGCAGCATT 1380 GACCTCCTGA GCTCAAGCCG TCTTCTCACC TCAGCCTCCC AAGTAGCTGG GACTACAGGT 1440 GCACATCACC ACATCCAGTT AATTTTTAAT TTTTTGTAGA GACAAGGCCT CACTATGTTG 1500 TCAGGTTGAT CTTGAAATCC TGGGCTCAAT TGATCCTCCC ACACTGGCTC TCTGGGATTA 1560 CAGGCATGAG CCACTGCACC CAGCCCCCTG AATCTTCCTT GACTTCATTC ACACCAGCCC 1620 TGCCTGTTTG CTGAAGGTTG CTGGAATCTG GCTGGATCAT CTTTCCAGGA AAGGGGGCTT 1680 ATTTGGGGTT TCAGGCAGGC ATATCAGCAC ATTCCTGTAT AAGACTAGGG GAGTTTCAGC 1740 ATATTCCAGG CTGACCTTTC CTTTCAGTTG CAGATCAGAC AGAGTCAACC TTAGTTTTAT 1800 TTAGTTGGTT TATTGTTGTT GTTTTCCCTC TGTGACATAG AAGCGTGCAC TTTGAGGGGG 1860 AAAAAAAATC CTACCTGTTT TACAGTTAGT TCCATGAGAA GCCAAACTAG TTATTAAAAG 1920 TAAGAAATAT TTTAAGTTGC TCAGCTGAAA TTTTAACAGC TCTTGTCTAA TCGTTAACAT 1980 ACAAACCTCC CTAACCAGAA TATTTGTGGG GGATGACTTC TTAACAGGAT CTAAAATCAG 2040 CAGTTTCCCA AAAAGCCTGT TAAAAATTAC ACATCTGGAA TTTTGTCCTA GTCTGACTAG 2100 GCTGCTGAAT TCCCTTTTGA TGTTTCCTGG GGGGTGGGGA AGAGATAAAT AGCCTGATTT 2160 CATTTAATGT AGTACATTTC TTTGAAATCT GGTGTCAAAT TTTGAGTATT TGCTGAAAGG 2220 TAGGGTGACC AATCATCCTG GTTTTCTTGG GATTGAGGGG TTTCCAAGGA CACAGGATTT 2280 TCTTTGATTT GGGAGGCCAA GTTGAGCTGA TCATCCTAAA AAGGAAACCC TAGTCCAAAT 2340 CACTCACAGG ACAGGTGAAG AAACTGAGGC CCAGCAAGAT GAAATCATTT GCCACCATAT 2400 TACATAGTTA GCCAACACTG ACTGCATTGC TGGGACCAGA ACCCAAATCT TCTAAGTCTT 2460 AGTTCAAAGC TCCACTGACC CACTTGACTT CTCCAAACTT AAGTTTGATG ACTGGTTTGT 2520 CGGTATTTGA CTGCTTTATT TAATTTATAT GTGAGCAGAG GAAAGCGATA GTCCAAGTAC 2580 ATTCTAATCA GTGATCATAA AGACACAGAT GTTCTAAAGC AACATAAAAG TAACATCTAC 2640 TGAACACCCA TGTTCATAAC AGCATTACTC ACAATAGCTA GAATGTGAAA GCAACCCAAA 2700 TGTTCATGGA TGGATGAATG GATAAGCCAA GTGTGGTATA TACATACAAT GAACTATGCG 2760 ATTCAGTCTT AAAAAGGAAG GAAATTCTGA CATTTGCTTC AACAAAAATG AATTCTGGGA 2820 CATTATACTA AGTCAAATAA GCCAATCACC AAAAGACAAA TTCTGTATGA TTCTACTTTT 2880 ATGAGGTACT CTATGAGTGG ATACTTACAG ATCTAAGATA TAAATACTAT ACTTAGAGTA 2940 TTTGTCTACT CTAAGTAGTC AAAATCACAG AGCCAGAAAG TAGAATGGTG GTTTGCTGTC 3000 AGCTTGAGGG AGGGAGGAAT GGAAGTTATT GTTTAACAGG AACAGAATTT CAGCTTTGTC 3060 AGATAAAGAG AGTTCTGGCT AGGCACGGTG ACTCAGGCCT GTAATCCCAG CACTTTGGGA 3120 AGCCGAGGTG GGCGGGTTGT TTTAGCCCGG GAGTTTAAGA CCAGCCTGGG CAACATGGCA 3180 AGACCTCATC TCTACAAAAA AAACAAAAAA ACAAAAAAAC AAAAATTAGC CAGGCTTGCT 3240 GATACATGCC TGTAGTCCCT GCTATTAGGG AGGCTAAAGT GGGAGGATTG TTTGAGCCCT 3300 GGTGTTTGAG GACGCAGTGA GCTATGATGT TGCCACTGCA CTCCCAGCCC AGGTGACAGA 3360 GCGAGTCTCA AAAAATAAAA GAAAGAGTTC TGGAGATGAA TGTAATGATG GTTGCACAAC 3420 AATATAAATG TACTTAATAA CACTGAACTG TACACTTAAA AATGGTTGAT AGTACATTTT 3480 ATGTTGGATC TATTTTATCA CATTTTTTTA ATGGAAAAAT AAAATAATAA CTACAAATAG 3540 CTCATCTATT CCATTGGTGC AATGTTTCTG TTAAAGAGGT CTGCAAAGTG CTTTGCAGCC 3600 ATTTATTAGC TTTGGGATGT TTTGTCAAAT CAAACCACAT TCTTTAGATA AGGAGTTTGG 3660 TTTGCTTTGA TATTTAGTGA CCTTCCCTTA GCTAGGGCAT AGAATTTCCA GATGTGCAAC 3720 ACTCCCAACT TCTAGCTGCA AGCTCACAGC CTGGCACATA GTAAGTGCTC CATAAACATT 3780 TTTTAAATAA ATAAATAACA GCAAGGACTA ATATTTATTT GAAGCATTTA TTCAGAGGTG 3840 GGTTGAACTT GAAGCTGGTG ACGCTTAAGC TTCAGGATGT CTCACTTTAA TAAGCCTTTT 3900 TCTAGACCTT GTGTGCGGGC GAGGGGAGGA CCTGAGCAAT GTGTTCACAT AGTCACATAT 3960 TCATATAAAA CTTGCAAAAG TAAGATTTAT CTTCTTTTCA TTAAAGAGGG CTTCCGAAGT 4020 TGTGTAGTCT TCAAGTCCCA TGAAACCCAA ATCTGTCCCT GTACTTACTG CCTTTCTAAG 4080 TACTCTATGA ATTCCTTTCC ATGGTTTCCT CATGCAATTC TCACAACAAC CCTATGAGGT 4140 AGAAGCTATT ATATTCACTT CTGAGATGAG GAAATTGGGC AGCTCCACCA TGGTTACCCC 4200 ATGAGGGAGT GATAGGCAAG GACTTTCACT CTGGCATTTG AGACTAACTC TACAACTCCA 4260 CTGAACACTA GGGATGGCCA AACCTAACTC TAGCTCATGT TAAATTAGGC ATGTAGCCAG 4320 GTGTGGTGGT GCGTGCCTGT AATCCCAACA CTTTGGAAGG CCGAGATGGG AGGATCTCTT 4380 GACCCCCAGA GTTCGAGACC AGCCTGGGCA ACACAGCAAG ACCTCATTCC TACGAAAGAG 4440 TTAAAAATTA GCCAGGTGTG GTGGTGCATC CCTGTAGTCC CAGCCAGTTG CGAGGCTGAG 4500 GTGGGAGGAT CTGTTGAGTG CAGGAATTTG AGGCCGCAGT GAACTATAAT TGCACCACTG 4560 TATTCCAGCC TGGGTGATGG ACCAAGATCC TGTCTTAGAA AAAAGAAAAA AAATTAGGTG 4620 TGGTCTTGGT AAATACTACA ATTTCACCTG ATGTAACTGT AATAGCAACA ATTGCATGAT 4680 TGGCTGGTCT TTAAAAATAA CCTGTGATTT GGGGAAAACA TTTATTTTAC AGGTTTTTTC 4740 CTGTCCCTAT AATACTCACT TCATATTTTT GTTTGGTAAG ATAGAAGGAA GTTTGGGAAA 4800 GGGGAAAATG AAAAGGGCAA GGCCAAAGAG GAGAAAGGAA CAGAGATGTC ATCCTATGTT 4860 AAGGAAGATT CTCCTCGCCC CCTCCACAGT TTCTTTCTCT TTCTTTTTGA AGGATGTGCA 4920 AGGGTGCTTT GTCTCTTGGG GAGTTCCACT CCCGTTTCAA CTGTTCTCTG AATCTGCTCA 4980 ACTTCTGCAT TAGAGTCCCT ATTTCTAGTC TGACAGTCCT ACAAGTCAAA GGGCAGAAAG 5040 GAATCTTTCC TGTAAACATC CTCTGGGCCA CTCCTGGAAA AGGTGACCAG CAACCACCGC 5100 TTCCTGTCTT TATTCTGACT CTTGGAGCAA ATAATACAGT TTTCTATTCC TCTAAGATTT 5160 CTTGGAGCCA ATAGGAGAAC AGAACTGAAA ACGTCATAGG ACTGAAAATA TCCTCCTATT 5220 GAGGATGCTG CTTTCTTTAG ATTCAGGTTC TCCGCTTTAA AAAGTCATTC CCACCCCTGG 5280 CTTCCACACA GATGCTGGGG ATACGCACTG TGCCTGGCAC TTAGGAAATG CTGCTCACTG 5340 ACTCCCACCT CCTCAGAGAG GTGCTGCCAT TAACCCAAAG ACAACCCCTC CCCAGTTTTG 5400 TGTCCCCCTC CCCCACTGCC CAGAGTTTTC TGTCTTGATT TCCCTATTTC TGACTGCAGT 5460 GCAGTTATCA CCCAGCTGGT CAAACCCCAG GGTCACTCTG CCCACCCTTC GCTTCCCTCA 5520 GACTTCATTA ATCACCAAGT ACCATGGGAT TTCCTTCCTA TTCATGCCCA TACTCATTCT 5580 CTGTTTTCCA TTTTCTTTGC TGATACTTTG TTCAATGCCC TGCTTATTTT GGGCCTGGGA 5640 CATTACAATT GCTTCCTGGC GGGGTTCCCT GCCTTTAGAG TCGCTCCCTG CTAAAAGTGG 5700 ATTTGTCATG TAGCTAACAA ATCTCAAGCT CCAGGACAGA TGCTTGTACC TAATTTTGTA 5760 TCTTGTGACT TTATATTCTC GATCTGCCCC ACCCCCTATC CATTTGGCAC TCAGCTGCCA 5820 GATTAATCCT TTTTACAATA GGTTTTATTT TTTGAGCAGT TTTAGATTCA CAGCAATATT 5880 GAGCAGAAAG TACAAAGAGT TCCTGTGTGT CTCGTGTCCC CAGACACACA CACAGCCTCT 5940 CTGATTATCA GCATCCCACA TCAGTATATT TGTTTCAGTC AATGAACCTA CATTGATACA 6000 TCATTATCTC CAGAAGTCCA TAGTTGACAT TGAGTTTAAT CTTTTAAAAA TACTATTCTT 6060 TCAGCTGGGC GTGGTGGCTC ACGTCTCTAA TCCCAGAACT TTGGGAGGCC AAGGTGGGTG 6120 GATTATCTGA GGTCAGGAGT TCGAGACCAG CCTTATCAAC ACGGTGAAAC CCCATCTCTA 6180 CTAAAAATAC AAAAATTAGC CAGGTGTGGT GGCGGGTGCC TGTAATCCCA GCTACTTGGG 6240 AGGCTGAGGA AGGAGAATGG CTTGAGCCTG GGAGGCGGAG GTTGCAGTGA GCCAAGATCG 6300 TGCCATTGCA CTCCAGCCTG GGCAACACAG CTAGACTCTG TTTCAAAAAA TAAAAATAAA 6360 AAATAAAAAA ATACTATTTT TTCATATCAC TGGTCTGCTT TAAAACTATT CATAAAAATG 6420 CTGACCATCA GGACATATTT CAGAATTCAA GGAAAAAATT GAAAAAATAA AATAAAATTC 6480 TGTCCATATC TCCAAAGTCT ATGTCCTTAC TTGGATATTC AAGGCTTTCC ACGATCTTCC 6540 CCAGCTTTCA ACCTGATTTC TCAAGAGTCA TCTGCGCATG CCCTTTGCAG GGGGTGCTCT 6600 TCACCGACTC CTACCCGCTG TCCCCATCAT CACATCTGTG GCTCTGCTAC ACGTAAAATC 6660 TGATTGAATT CAACTCCACA AAAATGTGCT GTGACTTACT TAATCTAGGA TGTCTATCTG 6720 CCTCCATTCT GACCATGAAA AACCCACCCA GTTTACTATG CCAGTCCACG AGCCCCTCCT 6780 GGCTGCAATC CTGTTTGCCT CAATAGCAGT AGTTTCTAGC TTGAGAGGGG TTGAAGTGGA 6840 CTAGTAAGAC TTTTAAAAAC AATAATAAAG TACAGGGAGG CCGAGGCAGG CAAATCACCT 6900 GAGATTGGGA GTTCGAGGCC AGCCTGGCCA ACATGGAGAA ACCTCGTCTC TACTAATAAT 6960 ACAAAATTAG CTGGGCGTGG TGGCATATGC CTGTAATCCC AGCTACTCGG GAGGCTGAGG 7020 CAGGAGAATC ACTTGAACCT GGGAGGCGGA GGTTGCAGTG AGCTGAGATT GCACCATTGC 7080 ACTCCAGCCT GGGCAACAAG AGCAAAACTC TGTCTCAAAA AACAAAAACA AAATAATAAA 7140 GTACAACATC TGATTGTCAA TTTTTTATTC TGCCAAATAA GAACTTAAAA AACAACTACC 7200 ACCATCACAG TATCTTATTT TAAAAAAGAC ATTTACTAAT CAAAAAGCAT AAAAGGCATA 7260 ATATCAGAAT AACTGTTGGT TCTTCAAATG TAATTCACTT AGCTTTAGGA AAAAAATCAT 7320 TTTTAAAAAA AATTGTATGA CTGTCTGAGG TACTGAAAAC TGTTCAGACT GGCATTTGGG 7380 AGTGATTCTA CAGTGCTTCT GGTCTCCACC ACCTGTTTCG CATTTAATCA CAGGCTGCCT 7440 TGGGGCACAT TTTCATTGTT GCCTCTCTAT TTAACTTCTT GTGCACATAT GTTATTTCCC 7500 CAACTGGAAG GTAAGCTTTA TAAGGAATCT GTAAAAGGAC TGCACGCTTA ACTTTCCAGC 7560 AAGGCTTTGC ACACAGAAAA TGTTCAATAA ATATTTGTTG AATGAATGAA TCAACCTTTT 7620 CTAAGCCTGT GCTAACCAAT AAATCTCCTC TTAATGAGAT CTGAGCGCCC CATCCTGAGG 7680 CAATTTCTCT CAACAGACTT CTTTAAAATG AATTATCCAG TACAAATTGC TTTACTTTTG 7740 AGTGAAGCCT AAAAATAAAA ATTGTTTAAA CCTGATATGA AAAGTAAACA GTTTTTTCCT 7800 CAGGGCAGTA GCAAGCCCCA ACAGGGAGGA GAATCAAGAC ACAAACACAC TTCTGTACCC 7860 GCCATTTAAT TGATCCTAGT TATTTTGGGC TTTGTTGGTA GGCATGCACA CAGTCCATGC 7920 TTCTGGCTTG ACTTGACTGC ATAGGGTGGT TGGCATTCTT TCTGGGGCTC TCACCCCTGT 7980 GCCTAAAGCC TCCACGATAA CCATGTTGTG CCTTTCCCTC TCTCTACTCG GGTAACTTGG 8040 AAAGAAAGGT TAGGAAGAAG CTTAACATCT GGCTAGCCAA GCCTTGGTTT TAGATTCCAG 8100 AGTTGATACA GAGCAATTCA GAAAAGTGTC TTTTGGATTT AAAGCATTGT TTTTGCTCAG 8160 GATCTCGAGT TACCTTCAAA AAATTTAAAT AAGATAAGGC CACATCCTTG CTTAAAACAT 8220 TCATCAACTT TCAATTCAAT TCCATTCAAC GGCTATTGAT TGAAGACCTG GCCCTGAAGA 8280 ACAGAGCCGG AATGCCAGGC CCTGTTCTAG ATGTTGGGGA TATGTCAGTA AACAAAGCAG 8340 ACAAAACTTT CTGCCTCACC GAAGCTTAGA GGGAGGTAGG AGTGAGGTGG GGGAGACAAA 8400 CAAGAAAGAT AATGAATAAA TAACATATTA TTTCTGTGTT AGAAGGTGAT AGATGCAATG 8460 GAAACTAATT GGAGCAAGGG GGTGTTGCAA TTGGGACGGG AGGGACAGAG GAGGCCTCGT 8520 TGAGAACGTG GGTGGAGCAA AGGCTTGGAG GAGGTGAAAG GTGTGGCCAT GAGACCATTT 8580 GGGAGAAGAG GAAATGCCTT CCATATCATG ACCTCACCCA GCACCCTCTC ACCCTGTGGC 8640 CCTCCCACAC GGATCTCCAG CAGCCCCTGC AGTCTCCTCC CCACCTCCAG GCTTCACACA 8700 CATTGTTTCA TCCTCAGGAC TGTATTTTCC TTCCCTGTCT CTTGACCAAC TCCTCATCCT 8760 TCCGACCTCA ATCTAAATGC CACCTCCTCT GGTGGGCTTT TTTTTGCTGC CCCTCATCCA 8820 TTATAACTTA GATGCCCTGC CACAGTCATA GCCCTCCCTT CAGATACTTA ATAAATACTG 8880 TTTGAATGAA TGAACAAAGA AAAGGGCTCA AAGCGGGTGT TGAGGACAGG GATTCTGACT 8940 CATTGATTTA TCCCCAGTGC TGGGCACATT GTTGAAGGTA TTTGGTAGAC TTTATCTTCA 9000 TAAATAAGCT CCATTATCAA GGATGGATAG AATGATTATG TTATGGCTTA CTTAAATTTA 9060 AGCATAATAA TACTATAAAC AAGATTTGTT AAAGGGGGAG TGAAGCATTA AATTGTGTTA 9120 CGGGGAATGA ATTCCCTCCT TCCTTCACTT TTTCCAATGA AGCAGGCCTT GGTTTCAGTC 9180 CTTGGCCCAG ACGAGCCCTT TTCAAGGAAC ATTTCCCACC AGTGACGGTG CCTTCCTGTC 9240 TGAGATCAGC ATGTCCTTCA ATTTATTCTG CAACTCAGTC AAATTAATTA AAACTAGATT 9300 TGTCCTGAGA GTTTGTTCGT TAAGATGTCA CTGTATATCA AATTCCCAAT TATCTGGGAT 9360 AATTAAAACA TCCTAACTTT TTCCCCGAAT TATTTATACT TTTGGGAGTA TCCCCTTGTA 9420 GGGTTCAGGA CACACTACCC CAAAATATGG CACCTTGGCA CTTCAGAAAA CCCCAGAGGC 9480 AGGAAGGTTA CTCTCACCTT CCCCTTGCCT TTCTCTTAGA AGCAGGTCAT AAAACCTTCT 9540 TTCCAGAGGT GCCCACCCTG TAGCCAGGGG GAAGGAACGT CCCTGTCTTT GAAGACACAG 9600 AGACACAGAG AAGAATCTGA ACAAACAAGC CTTGCTAAGT TCCCCCTAGT TTATTAGCAT 9660 TAGATCATAC AGTTTTGTCT AATCATCTCC ACAATCATCC ACTTATTCAT CAAACTTAGC 9720 ATAAAAACCC ACAGGTTTCT CTGTCTCTTT GGATCTTCAT TTCCGAAGCT ATGCCATATA 9780 AAACTTACAT ATTAAATACA TTTATATGCT TTTCTTTTTT TAATCTGTCT TTTGTTATAG 9840 ATGCCTCAGC CATGAACCCA GCAATGAGTG AGAAATTTTT CCTCCCTTAC ACTCCAAAGG 9900 TATATTTTTA TTGCTATTTG CTCAGGAAAT GCCATAAGGA TGATTTAACG ATTTCAAATC 9960 ACCACCTCAT TTGACATGCA TTTTAGGTAA CATAAAAATC ATGCAATATG ATTGAAACAA 10020 AAGAAATTAA TTAGAGCAAA GAGAAAAATA CAAGCAAGGC AGTAAAGTGA AACAAGAAAT 10080 AAAACCACTC ACCACTCACG ACACGGAAAT TCCAACTGTA AAGACTCAAG TCTTTTCTGG 10140 AGGGGGATCA CACATTTGGC TCTGAGCAAT GAAGAAAACA GACAAGTTAT AGGATTCACA 10200 GTGTTTTATA ACATACATAC CACGGTCTCA GGAGCCTTAA GACCTGAAAG ACGTTTCTCC 10260 CATATGTCCT CAAAAGGGAC ACTGATGTCA TGAATGACAC TTAAAGCAGA TGAGTTTCCA 10320 ATAGCTGTTT CTTATGGTAT CACTCCAGGA GCCTTTAACC TAGGGCCTAA TGACAAAGTG 10380 AGGTCCTTTA AAATTCAGTT CTCTGAGGGA ATGACATGAT GCAGTTCACA AATGAAGTTT 10440 TTTAAGTATC TGACTTGATG CACAGATAAA GTTTAAAATA TCTAAAATAT CTAAAAGAAG 10500 GCCAAGTGTT GTGGCTTCCA TTTGTAATGC CAGCACTTCA GGAGGCCGAG GTGGGAGGCT 10560 TGCTTGAACT CGGGAATTTA AAACCAGCCT GGGCAACATA GGGAGACCCT TTCTCTTTAA 10620 AAAGTGTAAA AATTAGCTGG GCATGGTGGC TCATGCCTGT GGTCCCAACT ACCCAGGAGA 10680 CTGAGGCAGG AGGATTGCTT GAACCCAAGA GGTCAAGGCT GCAGTGAGCT GTGATCACCA 10740 CCACTGCACT CGAGCCTGGG AGACAGAGTG AGCCTCCATC TTGAAAAAAA ATAAAAGAAA 10800 TAAAAGAAAA AGGAAAGGAA AGGGAAGGAA GGAAGAAAGA AAAAAAGAAA GAAAAGAAAG 10860 AAAGAAAGAA AAAGAAAGAA AGAAAGAAAG AAAGAAAGAA AGAAAGAAAG AAAGAAAGAA 10920 AGTTGGATGG CCTGCATCTC TCCCTAAATG TTGTTTTCTC CAATCAAACT TCCATAAGAA 10980 TTAAGGAGCA GAGAAGTCAA GGATAAATTG TCTGGCAGGT ACCCAACAGC TGAAACTCTA 11040 TACTTCTGAT TAGATGCGGA TGTACACCTA AGAACTTGGC ATCCACTTGT GAAAGTGAAG 11100 GTTCCTAACC AGGCCATGTA CTTGTATAGA CCTACGTCCT CAAAGAGGCA GACCACAGTG 11160 TACCCATGGG TAGGGGCCAG ATTTCCTTCA GGAAATAGTC CACAGTTGCT GTAACATGAC 11220 AATAAATGAA CAGCCAAGAT CCATGGAGTG GCCATGGTGT GGGACATAGA TAACAACCCT 11280 CCCACCAACA TTAGACACTG CACAGTTAGT TTTCTGTTAT CCTGTTTTGG TTTTATCATG 11340 TATACCTCCC CACCCATTAG AGTAGTTAGT TGAGAATTGA CTGTTAAAAA TGAAATCAAC 11400 CTGCCGAGAA AAAGTCATGT TGGATGAATC ACTGGGGCCC TAGGCTGTTG GCTTCATGTT 11460 TAATTTGGAT GCTTCCCAAT CCAATCTTGA GTAGGTCACC CCATATAGCT TCCTCCATCA 11520 GCAGGATGAT TTTGTTTTAG AAAATATGTA CACTTGGTAA ACTGTCAAAG TGAGTTGTAC 11580 ATATGGTATG TGTTGTTCAG AGGGAGAAAA TATTTTCAGC ACTACTTGAA GTCTTTATAC 11640 CTGACAATGC ATTAAGAATT CAACACAATA ATCTTATTGT TTTAGCTGTT GCTTTTACCA 11700 TTACTCATGC AGCATGACTG GGAAAAAAAT TAATGATCCC CCCCACCCCC ACAGTGTTTG 11760 GTGTGTGTGA GTTTAAAAAA AAAATCTTTT GGTTTGGGAT GAATGCGTCG AACAATCCAC 11820 CATCTGGTGT ACAAATATTT TTATAGACAC GAATCCAAAT ACCACAAAAT CAGTGCCATG 11880 GCTCAGGTTC TGTGAATCTT TTTCTGAGGC AGACTTTTTA TTAAATATGA TTATTCTTGA 11940 ACTATGAGAC TCTCTGCAGG AGCATTAAGA TTTAGCCTTG AGAACAAAAC TCTTTATGTT 12000 GACCAATATT TTTAAAAAGA TGGAAAGAAC TCTCTCTGGA GCTAATTTCA AGGAGGACAA 12060 AAAAGAATTT TGTTTTTGTT TTTGCTTTTT TGTTTACATA CTAAGCATAT ACAAACTGAA 12120 TCAGTGACAA CTTCTGTTAC ATTCCTGCTG TAATCCTGGC TAGTGGAAGA AGATAAGATA 12180 TCAGTAAGCT CTGCGGGCAT CAAGTTTCGG CCCTGTCAGG TGTAATCAGA ACCCTGGTCT 12240 TAAAACGAAG GCCTCCACTC CACCTCCTCA GGCAGAGGAC ACTTCATTCC CCAGCCCCAG 12300 GCACTGAGAG GAAAAGGAAG GATCCATCCT GTAAGAGCAA AATAAAACAA AATAGCAACA 12360 CTGGGTTTGT GCGTTCCCTT TAACTCTTGA CACCCTGGAA TTAATGCAAA GTGGTCTGTA 12420 TTTAATATCG AATTCCCTCC CCTCACAATG CGATAATGAC AAGAGATTTT TAGAAGGCGT 12480 GGAAATTAAG AAATTTTAGA AAATTAAGAT TCTCCTCTGA ACCTAATGTA AAGAAAATTG 12540 ATGAGTCTGT GCATTTGATG GGATTCCTAG GTCAGCACCA TGTCGTGAAG ACATTTTCTG 12600 AGATAGTGAG TTTGCTCAAA ATGTCACTCC AACTTTTAAA GCATGGAGAA AATTGCTTGT 12660 CAGTGAATGT ACCACTCAGA GCAAAATAGA ATTTTTATTG CTAGATTTCC TTTCAAAGTT 12720 AAAAATAAGG ATAAACAGAG CCAAACGGCT GTTTGGGGGA ATGTAGTGAT CTGGGGAAGA 12780 GAATGATGGC ATATCGTTGG AGCTTCCAGC TTTGCTAGTG GAACTCATTG GAATGTCCAT 12840 GAAAATCACC ACAGAGTTCA GACATAGTTC TTAACTGGCA AAACTGTCCT AAAATGACTG 12900 GACTCTGATG CAGCTGCCTT GGGAGAAGTG GGAGAAATAA CAGTCCCACT TCAGCGATCT 12960 GCAAACTAAG GTACAGTGGA AATTGAGCGG TCGGGCAAGG GTCACCAAAA CTCAGTGGTG 13020 AGCGGGAGAC AGGCCCAAAG AGCTGAGGAA GTGTAAACTC CAGTGATAAG GCGATAACTT 13080 GAGGAAATTA AAACCCCGTA GTGTGGGAAA GAACAATTAG CCAAGACAGA GGGGCAGGAA 13140 GGAATACAGA ATGAATTACA ATCAGAGGAA ACTAGCCAGC AACAAAAGAG ATGAACTGGC 13200 GGGGGCGGGG CGAGAGGGAC GGGAGAAGTG ACTTAAGAAT GCTGGCTTCT CTGGGTTCCA 13260 TCACCGCCTT CTTGTTAGGT CGCCGTCGCT GCGATCATGA TTTAACCCCT TCATGCCTCG 13320 GAGTGTCTAG CTCCAAGGCA GCTATCTTTA TCCATGAAGT TCTTTGAGAT TGTGCCACGA 13380 ATATGATGAA TTCCAGATAA GAATGACTGC ATCATTAGTT TAGAAAAAGT TACCCCCGCC 13440 CCTCCAAAAA AGACAGAAGT TTAAGCTTAT ATAGATTAGC AAAATATTTC CATCAGAAAC 13500 ATAAGAAGGA ACATGTAAAA CACAAGTATC AGCAAATGCA GATGTTTTCA GACCAAGAAG 13560 AAAGTGTTCA TGAAAATGAA ATATTTTAAA GGAAAACATG TAAAAGTGTT TCAAACTGAT 13620 TTTGATGACT ATCAGGATGA CCTAAGGGGA TGAAATGTCC TATAACTAGT AGGAAATGAT 13680 AGAAAAAAAG TATGATTGTT TTATGAAAAT AATAATTTGC TTATTTTAAG TCAATGAGTT 13740 TGTCACACAT GATTATGGGC ACGAGAGAAG ATATGCTATG AGCCCAAAAT TAAATTGTCT 13800 TTTACTTCAA TCCTAAAAAT CAGCAGGCAG AAAGCTAAGA GGAAGCTCTT CTTTAATCAA 13860 CCAAGATGCT AAAATCATGG AGAGAAAGGC AAAAAAGATA GACCACAGTA GCTAAGTCAT 13920 TCAAAAGAAG GGGGAGAGTT GATTATGTAG AATGAAGTGG AATGAAGATG CTAAGTAGGA 13980 GTAGAAAAAC ATGATACTAT AACAAAGGGT TGATTGAGCA AACAAAGTGG GTAATAAGGC 14040 AAATTAAACA TTCTTATAAA TCCTGTGTCC AGGAAATGAA TTAACTGCTC AGACTAATAA 14100 ATGAAGAAGC ATCACACAGA AGATAATGAT TAAATGTCAC CATGGGAAAA CAGAAGGTTC 14160 CCGGTTTATA AAACCAGCAC GCTTAAAAAG AAGAAAAGGG TGGGGGCATT TGAAACAATA 14220 CTAAGAGGCT TTAAAAGTGA ACTGAAAAAA AAATGTAAAG TAGACAGTGA TGGAAGGACA 14280 GCCTTAGAAG ACACCTCAAT GATACAAGAT TCTTTAAATA TCTTAAAGGG ATTGTGGGTA 14340 AGGAGGAGCA TCCAGGAAAT TGAAACATTA AACTTGGGTT TATTTTAATT TATTTTACTT 14400 TAATTTTTTG GTCTTGCCTT CATGAGGCCA ATAAATGTAC CAGAAATGGA AACAGTATCA 14460 GAGAGTGATA AATTAAGAAC AATGAGGAAT TCGCTTCCAA TAAATTAAGT AACTCAAGAA 14520 AAGACAACTC CTGAGTGGGA AGAAAAAGCT GCAGAGATTA ATACTGCCTT CATGCAGCAT 14580 TTGGATGGCT CCTAGGAATC ATAAAGATAC CTGGGGAAAT CAGAGCCAAG TAAATCTAGT 14640 ACCTTTCAAA AAAAAATGGA CTACGGAGGA AGCAGAAAAA TGCTAGCCTT GCAACTCGGG 14700 AGCAATTGAA ATATTTAAAG TATAGATAAA GCAACCAAGG TGGAATTACC AAATACCTAG 14760 AAATATATGA GTTCAGCAGA CAAAACAATC AAATTTTAGG GAAAGTGACC TCCGGAATAA 14820 AATCCTTATA GAAGTTTTCA GGCTTTTGAA TTTTGGCCAC TATACTACAG TTTATAGAGA 14880 AGATGAATAA ATGGACATCT ATTAGCAACA TCATGATATT CTGCAAATGG CATTTGTTAA 14940 CTAACATCAT AGAATACAGA TTGATAAGGA GGAATTGGAA GAGATTAAAC AGTCCTCTCC 15000 CCCTGGAGGT GCTGACATCA GCATAGATAC AAAAGTATCC ATAAGCGTAG GCATCCAATG 15060 ACCGGAAAGC TAGTGGCATC TGTCACACAT GCATTGTACA ATTGCAATGC ATTGTATGCG 15120 TGAGCAAGAG CATCTCAATC TCAGATTCAT TTAAACAAAT AAGTCATCAC AGAAATAGTA 15180 CCTATGAAGA AATCCTTGAA GAGGTTTTGG AATGAATGGT TTGCTGGGCA GGCAGGATAT 15240 TTCTGATACA AGAAGAGCCT CTGAGAAGGC CCACAGCCAG GAGTGGGAAA TAGGGCTGAG 15300 GAATCATGAA CAGGGCTGAC AGAGCATAAT ATTCGTAAGA AGTGATGGGA AAGATTAGGT 15360 AGCCTATAGT AGGAGACAGA TTTGAGCATG GGCTTTGGAG TGAGACAACC TGGTTTGAAG 15420 CCTAGCTCCA TAGTGGTATA ATCTCTCCCC CACCCCCACC CCCACCCTGA CCTCTGTGTG 15480 CTTTGGTCTC TTCATCTCAA AATTGGAATT TTAATATACT TACCTTAAGG ATTGTGCTAA 15540 GAGTTAAGTG AGATGTTCTG TGTTCAAGCA CCTAGAAAAA ATAAGAACTC CAATATTAGC 15600 TATTGCTGTG AGTGAATTGT AGTCAGTCCA CAGATGATAA CACTCGCCTT CCTCATTTCC 15660 TTGGGGTCAT CTCTTTTGAC TTTCTGCTGC CTTTTCAAAA CTTTTACACT GTCTAAGGAC 15720 AACAGCCCTA CCTGGCTCTC TCACTCTAAG AGATGGTGGG AAGGACAGTT TCACTCTCGA 15780 TTTCCCTGTT CTCCCCTCAA AACACACTCT TTCTTCTTAG CCCCCTCTGC TGTTTCTGAG 15840 AACACAGTGC CCCATTTCTT TCCAAAGCTA AAACCTCTCT GGCAACAGAG AACCCGACTG 15900 TTATGGATTC AGCAGTTGAC GGTTGACCTC CAGCAGGTTG GTGCTCCATC AGTAAGCCCA 15960 TTCCTCTCTC CCAGCTGCAG TAACTCCTTC CTGTCAGCCT CCAGCCCTGC TCAAGTCTTC 16020 TCTGGCTCTG TGCATTTCTT CCTCCAATGT GCAGAGCCAA CACCACCCAC TTCTTTCCTT 16080 CCCTGCATAA ATGAAACTCC CCTCTCTCTG ATTTTTACTC CCCCTTCCTC TGCTGAAGCA 16140 GCTGGTTTGA TGGCCACCAA AGGAGAAAGT TTTTCTCCAT CTTATTCTAT TCTAGTTTTT 16200 TGTGATTCTG TGTTACCTCT ATTGACAGAT TGTTTTCTCT TTTCTGATGG TTTCTTTATA 16260 GTCTTCTTTT GCTTTGCTCA GGTTGTTCCT GTAAGTATCT CCAGGGATTC TAGACTTGGC 16320 TTGTTCAGTT TCTCACACTG TACTGAACAA CCTCATGTAA ACCTTCAAGC CCATGATTTA 16380 TCATTTCGTT GTTATTGTTG TTGTTTTTGA GACAGAGTCT CACCCTGTTG CCCAGGCTAG 16440 AGTGCAGTGG CCCGATGAAG GTTCACTACA GCCTCGACCT CCTGGGTTCA AATGATTCTC 16500 TACCCTCAGC ATCCCAAGTA GCTGGAACTA CAAACACACG CCACCATGAC TGGCTAGTTT 16560 ATTTATTTTT CTGTGGAGAC AGGCTCTCAC TATGTTGCCC AGGCTGGTCC TGAACTCCTG 16620 GCCTCAACTG ACCCTCCTGC CTTTGCCTTC CAAAGTGTTA GAATTACAGG CAAAAGCCAG 16680 TGCACATGGC CATTATTTAT CATCTCTCTG CAGGTCATTC CTTGACTATC CTTCTGAGGC 16740 TGGAATTTCC AATTGCTTTT TGAAATTCTC ACACCATTGC CTTTTCATTC ATTTATTCAT 16800 CCACTCAAAA ATATTTATTG AGTGCTACCG AAACATGTTT AAAACTATCT ACTTAAATAA 16860 AATAAAAAAT AAAAAAATAA AAAAAAAAAC TATCTAATTA TCTCTCTCCA TCCCCACTCT 16920 CATCTGCATT TTGTCCTGCC TTTTCTCTGG GTAAATGATA TCCTTTTCTT AGGAGCAGAA 16980 GCTAATTTTA TTTCTTTGTA ATCTCCCAAA GTGACCTAGT ATAGTTTCTA GAACTAAATG 17040 GGACTCTATA AATACTGTTG AATTATATTG AGCTGAAATC ATACATGAAG TGATAGACAG 17100 TTATGAGAAG GACCTTAGAG GACACACATC TATTCATTCT TTGGCAAAAA CACAAATAGA 17160 CTCAGTTATC AATTAATACC TCTCTTGCAC TAATTTTACT TTTAGCATTA AGATTCTAAA 17220 ATTCTATACA 17230
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