Tag | Content |
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EnhancerAtlas ID | HS074-00108 |
Organism | Homo sapiens |
Tissue/cell | GM19239 |
Coordinate | chr1:12231310-12234300 |
Target genes | |
TF binding sites/motifs | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
FOXP1 | MA0481.2 | chr1:12233024-12233036 | TTCTGTTTACTT | - | 7.22 | FOXP2 | MA0593.1 | chr1:12233025-12233036 | TCTGTTTACTT | - | 6.32 | GATA2 | MA0036.3 | chr1:12232427-12232438 | TTCTTATCTGT | + | 6.14 | Gata1 | MA0035.3 | chr1:12232427-12232438 | TTCTTATCTGT | + | 6.62 | Nr5a2 | MA0505.1 | chr1:12231941-12231956 | TCTGACCTTGACCTT | - | 6.94 | RORA | MA0071.1 | chr1:12231949-12231959 | TGACCTTGAT | - | 6.02 | Stat4 | MA0518.1 | chr1:12233725-12233739 | CGTTTTCCTGGAAG | - | 6.23 | ZNF263 | MA0528.1 | chr1:12231491-12231512 | TCTCCTTCCCTCGCTTCCTTC | - | 6.08 | ZNF263 | MA0528.1 | chr1:12234206-12234227 | TTCTTCTTCTTCTTCTCCTTC | - | 6.52 | ZNF263 | MA0528.1 | chr1:12234209-12234230 | TTCTTCTTCTTCTCCTTCTCC | - | 6.7 | ZNF263 | MA0528.1 | chr1:12234212-12234233 | TTCTTCTTCTCCTTCTCCTTC | - | 7.12 | ZNF263 | MA0528.1 | chr1:12234215-12234236 | TTCTTCTCCTTCTCCTTCTCC | - | 7.13 | ZNF263 | MA0528.1 | chr1:12234221-12234242 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234227-12234248 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234233-12234254 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234239-12234260 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234245-12234266 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234251-12234272 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234257-12234278 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234263-12234284 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234269-12234290 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234275-12234296 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234218-12234239 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234224-12234245 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234230-12234251 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234236-12234257 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234242-12234263 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234248-12234269 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234254-12234275 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234260-12234281 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234266-12234287 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234272-12234293 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234278-12234299 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 |
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| Number of super-enhancer constituents: 31 | ID | Coordinate | Tissue/cell |
SE_00369 | chr1:12226565-12247198 | Adipose_Nuclei | SE_01471 | chr1:12232095-12234188 | Adrenal_Gland | SE_04546 | chr1:12232368-12233932 | Brain_Anterior_Caudate | SE_06521 | chr1:12231395-12234253 | Brain_Hippocampus_Middle | SE_09154 | chr1:12224797-12249846 | CD14 | SE_10696 | chr1:12231624-12233979 | CD19_Primary | SE_11902 | chr1:12231048-12236114 | CD3 | SE_14553 | chr1:12231008-12236205 | CD4_Memory_Primary_7pool | SE_15480 | chr1:12231304-12235464 | CD4_Memory_Primary_8pool | SE_16369 | chr1:12231214-12235920 | CD4_Naive_Primary_8pool | SE_16946 | chr1:12231228-12235850 | CD4p_CD225int_CD127p_Tmem | SE_17650 | chr1:12231292-12241643 | CD4p_CD25-_CD45RAp_Naive | SE_17827 | chr1:12231021-12246713 | CD4p_CD25-_CD45ROp_Memory | SE_18389 | chr1:12226183-12250288 | CD4p_CD25-_Il17-_PMAstim_Th | SE_19117 | chr1:12225970-12243644 | CD4p_CD25-_Il17p_PMAstim_Th17 | SE_20048 | chr1:12231058-12236137 | CD56 | SE_20873 | chr1:12231198-12236438 | CD8_Memory_7pool | SE_22347 | chr1:12226250-12242299 | CD8_primiary | SE_26251 | chr1:12232165-12234254 | Duodenum_Smooth_Muscle | SE_27503 | chr1:12231615-12234368 | Esophagus | SE_30788 | chr1:12232018-12234343 | Fetal_Muscle | SE_32030 | chr1:12231844-12234207 | Gastric | SE_41498 | chr1:12232230-12236136 | Left_Ventricle | SE_42336 | chr1:12231389-12236106 | Lung | SE_48967 | chr1:12232188-12234263 | Right_Atrium | SE_50250 | chr1:12231283-12234299 | Sigmoid_Colon | SE_52522 | chr1:12231293-12236092 | Small_Intestine | SE_53313 | chr1:12231250-12236109 | Spleen | SE_55394 | chr1:12232096-12233341 | Thymus | SE_55394 | chr1:12233345-12234247 | Thymus | SE_61096 | chr1:12184746-12245090 | HBL1 |
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| Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | Number of disease enhancers: 6 | Chromosome | Start | End |
chr1 | 12232096 | 12232448 | chr1 | 12233600 | 12234159 | chr1 | 12231693 | 12231881 | chr1 | 12233531 | 12233800 | chr1 | 12233800 | 12234000 | chr1 | 12234000 | 12234197 |
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Enhancer Sequence | TCCACCTGCC TCGGCCTCCC GAAGTGCTGG GATTATAGGC GTGAGCCACC CCACCCAGCC 60 CCATTCTCAC TTTTAAGCCA TGCTTTTCTG TCCTCAGATG TGCTGCACAC ACACCTGCTC 120 CAGGGCCTTT GCACTTGCTT TCCCCATCAC CTCCAATACT CCTCCTGCTG ACGTCTCTTG 180 GTCTCCTTCC CTCGCTTCCT TCTGCTGAAG TAGACAATCC TGCCTGTAGG TGCTCCCTGC 240 CAGGCACTCT CACTCCCTGA CCTGCTTTGT ATTCCTGTAT AATGCTCTTG ACCTATTCTA 300 TTTATTTCAC TTTTATTATG TCTTCCCACA AGATTGTAAG TACCGTGAGG ACAGGGACTC 360 ATTCACCACT GTAGACTCTA GCCTAGAAGA GGGTTTTTCA GTCAGTGCCT CTGACTTTAA 420 TTCTTTGTTG TGGGGCTGTC CCGTGAGCTG TAGGATGTTT AGCGACATCC CTGGCCTCTA 480 CTTATTGGAT GGCAGTAGCG CCACCCTCCC TCGTGACAAA AATATCTCCA GATATTGCTA 540 AGTGTCCTTT GGGGTTGGGG GATTGCCCCT GATTGAGAAC CACTGGCCTA GGACAGTGCC 600 TGGCACATAG TAAGTGTTCA AAAAATATTC ATCTGACCTT GACCTTGATA ATGGCCCTGT 660 TTTACAGATG AGACGGGGGT TTGAAAAGTC AGTGGTGGCA GGGTGGGGTT CTGTTTGCCT 720 CCATCTCTTG GGGTATTTTT CTGGGCTCCT CTTCCCATTG AGTGGTGTCT GCTGAGGTTA 780 GGGGTCCTCT CCCCAAATTG CTCACCCCCT CGACATCCCT CGTGTAGTGA GGGATGGGGC 840 CACTCACTGA CGGTGACTCA GGGCCCCAGA ATGCATGTGA TTTACCCAGA AGCGGGCAAG 900 GAGGGAAGCT GGGGTTTGGG GTGCCGGGGA TGAACAGGAA CAAAGGAGAG GCGCTGTGGC 960 TCCCCGTTCT GGACCCTCGT CTGGCCACAG GGAAGCAGCA CTGATGACTC TGGGGAAAGG 1020 CCCCGGCCTC TGAATCAGAT AAACCTCAAG TCGCTGCTCT GCTGTTTTAC TGGCTGTGTG 1080 ACCTGGGCAA GTCTTTCTAT CCCTCGGAGC CTCTGTGTTC TTATCTGTAA AATGGGAGTA 1140 ATCCTAGCCT CACGGGCTGG CTGTCAGGAT TAAAAGTGCT TTCTAATCCT GGCATTGGCA 1200 GCTATTTGAG CCATTGGTGG CTTTGCAGGT CTGACCCGAC TCTCTGGGCC ATGGGGTGGT 1260 GCTCGGGCCT AGGTGGGGAC CCCTGTGGAG TCAGACTGTC TGCTCTGAGC CCCAGGGCCC 1320 TGAAGCTTGG GTGGCAGCCC TGCAGTTGCC CAGAGTTCCT GTCTAAGTGG CTTTGTTGCC 1380 CATCATCTCA GAAAGCAACT TCTTTCCTCC CTGCCTTTTC CTGTCTGTGC TTCTGCCCCA 1440 GTGCCCCCTG GCTGGGCTCT CAAACCCACT GCTTGACAGC CTGGTCTTAG GACACTGTAT 1500 TGTGGCAAAG GCTGTGGGGT CAGGATATCC CCTCCCCTCC CTTTGCCACC CCTTTTAGTG 1560 AGTAACAGGT GCTGTGTGTT TTGGGGATGA GTGAAGGGTA CATTTGGTGA AGCACAGAGA 1620 GAGTGCACAA GGCTTCAGTT TGCAAGATGG GCACGGGAAG ATTCCAGGCC ATCTCCAAAA 1680 CCTCTTCCAT CTCCAACCTC TGTGCTGCTG AAGGTTCTGT TTACTTGTGA CCCTGAGAAG 1740 GGGATGCCCT ATGGGGGCTC TTCTGAGATC ATGCTGTCCA TTTTCCTGCC TCCAAGTGAC 1800 TTCTAAGACA GCATGGCTCT GAGGAAGGAG CACTGACTTG GGTGTTGGGA GATCACAGTT 1860 CCCATCTGAG CACCGTCACT GGCTTGCTGT GCTACCTTGC TTGGGTTACT TAACCTCTCT 1920 GGGCCTAAGC ATCCCTATCT ATGAAACCTA ACAACCCTGG TTCCAATGCT TTCCTAGAAT 1980 ATTGGGGAAG TGTCGGCTTT GAGTATACTT GACAAAGGCC ACAGATTGGG GGTGGGGTAT 2040 ATAAAAGTCT ACAGGAAGGA GAGCCCAGGA CTCCCCACTG TCAATATCTT GGTTCCCCAG 2100 CTTCTCTTCT TCTTGCTGAC CTCAATCTCA CTTGCTTTGG GTGGATTGAT TTCCTGACTC 2160 AGGCTCCAGG GCCATCAAGA ATTCACGGCT GCCTTTCAGC CTTCATGAAG GACATGGTGG 2220 AGCTCCTTAG GCAGAACTGG GGTTTGTGGA TGTCCTGCCT CTCTGCCCCT TGGTACCTAG 2280 GTGGCACCTT TTCAAGTTCG GGAGCTAGAT CCTTTCCCCT TCCCCACACT GTAGGAAAGT 2340 CCTTACTGTA GGCAGGCGCT GCAGAGCCTG CTGTCTGGGA ACCCACAGGT TCAAGGAAGC 2400 CTTGAGCAGG AAGGGCGTTT TCCTGGAAGA AGCCCTTTGT CGCTGGTAAT GGGTGCAGGC 2460 TGCTCTGACC CGGTTCTGAG TCCTGCCCCC TTCCAGGCCT AGGGCTTTGG GCCTTGATCA 2520 CCTCTGCTGA GTAGCTGACT GCGGGGCTGG GGCTCTGATG CTCAGGACCC ACCTCTCTGG 2580 GACCCACAGT CTTTTTCCAC TGTGGCGTGT AGTGATGTCA CAGGTGGCAG TGATGTCACT 2640 GTGGTTTGAG GTACTTGGCT GTGAGCCCCG GAGGAGGAAG TGTCTGTTCG CTGATGGGGG 2700 GTTGGAAGAG ATCATTGACT TCTGCCCCAA GCGTGAGCCC CAAGTGTGCA GGGGGGAGTG 2760 CGGGGGGAGG GCTGTTGGCG GCGCATCCCA GGGCTCTGGC TCTGCCCTTG CATCTAGCCT 2820 GTCTTTCCTG TGGGCTGTGA CAAGCCACTC TGCATCTCTG AGACTCCATT TCTTCTTCTT 2880 CTTCTTCTTC TTCTTCTTCT TCTTCTTCTT CTCCTTCTCC TTCTCCTTCT CCTTCTCCTT 2940 CTCCTTCTCC TTCTCCTTCT CCTTCTCCTT CTCCTTCTCC TTCTCCTTCT 2990
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